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Multiple Choice
Often, Cdks have to be dephosphorylated to become activated.
A
True
B
False
Verified step by step guidance
1
Understand the role of Cyclin-dependent kinases (Cdks) in the cell cycle. Cdks are crucial for the regulation of the cell cycle, and their activity is tightly controlled.
Recognize that Cdks are activated by binding to cyclins, which are proteins that regulate the progression of cells through the cell cycle by activating Cdks.
Learn that the activation of Cdks is not only dependent on cyclin binding but also on specific phosphorylation and dephosphorylation events.
Identify that Cdks are initially phosphorylated at certain inhibitory sites, which keeps them inactive even when bound to cyclins.
Understand that for full activation, these inhibitory phosphates must be removed by specific phosphatases, leading to the dephosphorylation of Cdks, which is a key step in their activation process.