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Multiple Choice
Which of the following histone proteins do not form dimers that make up the nucleosome core?
A
H2A
B
H2B
C
H3
D
H4
E
H1
Verified step by step guidance
1
Understand the structure of the nucleosome: The nucleosome is the fundamental unit of chromatin, consisting of DNA wrapped around a core of histone proteins.
Identify the histone proteins involved in the nucleosome core: The core is made up of histone proteins H2A, H2B, H3, and H4, which form dimers and then assemble into an octamer.
Recognize the role of histone H1: Histone H1 is not part of the nucleosome core. Instead, it is known as the linker histone, which binds to the DNA between nucleosomes, helping to compact the chromatin structure.
Differentiate between core histones and linker histones: Core histones (H2A, H2B, H3, H4) form the nucleosome core, while H1 stabilizes the structure by binding to the linker DNA.
Conclude which histone does not form dimers in the nucleosome core: Since H1 is a linker histone and not part of the core, it does not form dimers that make up the nucleosome core.