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Multiple Choice
Which of the following proteins is a transcription factor that activates genes to promote entrance into S phase?
A
Mitogens
B
RAS-MAPK
C
PI3K-AKT
D
E2F
Verified step by step guidance
1
Understand the role of transcription factors: Transcription factors are proteins that help turn specific genes on or off by binding to nearby DNA. They play a crucial role in regulating the cell cycle.
Identify the phases of the cell cycle: The cell cycle consists of several phases, including G1, S, G2, and M. The S phase is where DNA replication occurs, and the cell prepares for division.
Learn about the G1 to S phase transition: This transition is a critical point in the cell cycle where the cell commits to DNA replication. It is tightly regulated by various proteins and signaling pathways.
Explore the role of E2F: E2F is a family of transcription factors that are key regulators of the cell cycle. They are responsible for activating genes necessary for the progression from G1 to S phase.
Connect E2F to the S phase entry: E2F transcription factors activate the expression of genes required for DNA synthesis, thereby promoting the cell's entry into the S phase. This makes E2F crucial for the transition from G1 to S phase.