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Multiple Choice
Chargoff's rules state that…
A
A purine always pairs with a purine
B
A pairs with C and T pairs with G
C
A pairs with T and C pairs with G
Verified step by step guidance
1
Understand Chargaff's rules: In DNA, the amount of adenine (A) is equal to thymine (T), and the amount of cytosine (C) is equal to guanine (G). This is because A pairs with T and C pairs with G.
Recognize the base pairing: Adenine (A) is a purine and pairs with thymine (T), a pyrimidine. Cytosine (C), a pyrimidine, pairs with guanine (G), a purine.
Identify the error in the statement: The problem incorrectly states that a purine pairs with a purine and that A pairs with C and T pairs with G.
Correct the base pairing: According to Chargaff's rules, A pairs with T and C pairs with G, maintaining the purine-pyrimidine pairing.
Apply this knowledge: Use the correct base pairing rules to solve problems related to DNA structure and replication, ensuring the complementary strands are correctly matched.