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Multiple Choice
The position of nucleosomes on a region of DNA can never change.
A
True
B
False
Verified step by step guidance
1
Understand the role of nucleosomes: Nucleosomes are the basic unit of DNA packaging in eukaryotic cells, consisting of a segment of DNA wound around a core of histone proteins.
Recognize the dynamic nature of chromatin: Chromatin, which includes nucleosomes, is not static. It can undergo structural changes to allow access to DNA for processes such as transcription, replication, and repair.
Learn about nucleosome remodeling: Nucleosome positions can be altered by chromatin remodeling complexes, which use energy from ATP hydrolysis to reposition, eject, or restructure nucleosomes.
Consider the biological significance: The ability to change nucleosome positions is crucial for regulating gene expression, as it can expose or hide DNA sequences from transcription factors and other DNA-binding proteins.
Conclude with the correct understanding: Given the dynamic nature of chromatin and the role of remodeling complexes, the statement that nucleosome positions can never change is false.