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Multiple Choice
Which of the following transposons still jumps in the human genome?
A
L1 LINE
B
L2 LINE
C
L3 LINE
Verified step by step guidance
1
Understand the concept of transposons: Transposons, also known as 'jumping genes', are DNA sequences that can change their position within the genome. This can create or reverse mutations and alter the cell's genetic identity.
Identify the types of transposons: In the human genome, there are two main types of transposons: DNA transposons and retrotransposons. Retrotransposons include LINEs (Long Interspersed Nuclear Elements) and SINEs (Short Interspersed Nuclear Elements).
Focus on LINEs: LINEs are a type of retrotransposon that can copy and insert themselves into new locations in the genome. They are autonomous, meaning they encode the proteins necessary for their own transposition.
Determine which LINEs are active: In humans, the L1 LINE is the only known active LINE that still retains the ability to transpose. L2 and L3 LINEs are considered inactive or non-autonomous, meaning they have lost the ability to jump on their own.
Conclude with the active transposon: Based on the understanding of LINE activity, the L1 LINE is the transposon that still jumps in the human genome.