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Multiple Choice
The citric acid cycle requires oxygen indirectly, because oxygen is necessary for what to occur?
A
Replace FADH
B
Replace GDP
C
Replace ADP
D
Replace NAD+
Verified step by step guidance
1
Understand that the citric acid cycle, also known as the Krebs cycle, is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats, and proteins into carbon dioxide.
Recognize that the citric acid cycle itself does not directly use oxygen. However, it is closely linked to the electron transport chain, which does require oxygen.
Identify that NAD+ is a crucial coenzyme in the citric acid cycle. It acts as an electron carrier, accepting electrons and becoming reduced to NADH.
Realize that NADH produced in the citric acid cycle is used in the electron transport chain, where it donates electrons. Oxygen is the final electron acceptor in this chain, allowing the regeneration of NAD+ from NADH.
Conclude that without oxygen, the electron transport chain cannot function, leading to a shortage of NAD+, which is necessary for the citric acid cycle to continue. Thus, oxygen is indirectly required to regenerate NAD+ for the cycle.