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Multiple Choice
Vesicle fusion requires all but which of the following?
A
T SNARES
B
V SNARES
C
Trans SNARE complex
D
Rab GTP proteins
Verified step by step guidance
1
Understand the role of SNARE proteins in vesicle fusion: SNARE proteins are essential for the fusion of vesicles with target membranes. They are categorized into T-SNAREs (target membrane SNAREs) and V-SNAREs (vesicle SNAREs).
Identify the function of T-SNAREs: T-SNAREs are located on the target membrane and are crucial for recognizing and binding to V-SNAREs on the vesicle membrane.
Identify the function of V-SNAREs: V-SNAREs are located on the vesicle membrane and interact with T-SNAREs to facilitate the docking and fusion of the vesicle with the target membrane.
Understand the Trans SNARE complex: This complex is formed when T-SNAREs and V-SNAREs interact, bringing the vesicle and target membranes close enough to initiate fusion.
Clarify the role of Rab GTP proteins: Rab GTP proteins are involved in vesicle targeting and docking but are not directly required for the SNARE-mediated fusion process itself. They help in the initial stages of vesicle transport and positioning.