Multiple Choice
Which of the following property is false regarding supercoiled DNA?
4. DNA, Chromosomes, and Genomes
Helical Formations of DNA
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Which enzyme is responsible for repairing supercoiling through double strand breaks?
A
Topoisomerase Type 1
B
Topoisomerase Type 2
C
Topoisomerase Type 3
Verified step by step guidance1
Understand the concept of supercoiling: Supercoiling refers to the over-winding or under-winding of a DNA strand, and is an important aspect of DNA structure that affects its function and replication.
Learn about the role of topoisomerases: These are enzymes that help manage DNA supercoiling by making temporary cuts in the DNA strands to relieve tension and then resealing the breaks.
Differentiate between types of topoisomerases: Topoisomerase Type 1 typically makes single-strand breaks to relieve supercoiling, while Topoisomerase Type 2 makes double-strand breaks.
Identify the enzyme responsible for repairing supercoiling through double-strand breaks: Since Topoisomerase Type 2 is known for making double-strand breaks, it is the enzyme responsible for this specific function.
Review the function of Topoisomerase Type 3: Although not directly related to double-strand breaks, understanding its role can provide a broader context of topoisomerase functions in DNA metabolism.
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