Problem L2.3
Drugs with anticholinergic side effects block ACh receptors in the peripheral nervous system, including those on digestive organs. Predict the effects such drugs would have on motility and secretion on the specific organs of the digestive system.
Problem L3.1a
Mr. Williams presents to your clinic with a complaint of abdominal pain in the right upper quadrant. He says that the pain worsens when he eats, particularly when he eats fatty meals. He has noticed that his stool has been an unusual clay color recently. You perform an ultrasound of his abdomen and find that gallstones are blocking his common bile duct, preventing bile from entering the duodenum.
Why are his symptoms worse when he consumes a high-fat meal? Would you expect his symptoms to worsen or lessen when he consumes a meal consisting only of carbohydrates? Explain.
Problem L3.1b
Mr. Williams presents to your clinic with a complaint of abdominal pain in the right upper quadrant. He says that the pain worsens when he eats, particularly when he eats fatty meals. He has noticed that his stool has been an unusual clay color recently. You perform an ultrasound of his abdomen and find that gallstones are blocking his common bile duct, preventing bile from entering the duodenum.
You test Mr. Williams's stool and find high amounts of undigested fats. Explain this finding.
Problem L3.1c
Mr. Williams presents to your clinic with a complaint of abdominal pain in the right upper quadrant. He says that the pain worsens when he eats, particularly when he eats fatty meals. He has noticed that his stool has been an unusual clay color recently. You perform an ultrasound of his abdomen and find that gallstones are blocking his common bile duct, preventing bile from entering the duodenum.
Explain why his feces have become a clay color instead of a normal brown color.
Problem L3.3
Individuals experiencing prolonged vomiting lose a great deal of hydrochloric acid with the vomitus. Predict the effect this loss of acid will have on the pH of the blood. How will the respiratory system respond to the change in pH?
Problem L3.2a
A surgical procedure known as gastric bypass involves creating a small upper stomach pouch and attaching part of the small intestine to this pouch, “bypassing” the rest of the stomach and part of the duodenum.
Ms. Anthony has undergone gastric bypass. She goes out to dinner and eats an extremely large meal. Explain what will happen in her small and large intestines following this meal.
Problem L3.2b
A surgical procedure known as gastric bypass involves creating a small upper stomach pouch and attaching part of the small intestine to this pouch, “bypassing” the rest of the stomach and part of the duodenum.
How would bypassing a significant portion of the stomach affect absorption of vitamin B12? Explain.
Problem 1
Trace the pathway that food takes through the entire alimentary canal, from the oral cavity to the anal canal.
Problem 3
Which of the following is/are absorbed in the small intestine by the Na+/glucose cotransporter?
a. Glucose
b. Galactose
c. Fructose
d. Both a and b are correct
e. All of the above are correct
Problem 4a
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
The mucosa from the stomach to the anus consists of an inner layer of stratified columnar epithelium.
Problem 4b
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
The muscularis externa of most of the alimentary canal consists of inner circular and outer longitudinal layers of smooth muscle.
Problem 4d
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
The mucosa of the esophagus, pharynx, and oral cavity contains simple squamous epithelium to protect it from abrasion.
Problem 5
The primary hormone that triggers the secretion of pancreatic juice and bile is:
a. Gastric inhibitory peptide
b. Cholecystokinin
c. Motilin
d. Somatostatin
Problem 7
How does absorption of lipids differ from absorption of carbohydrates and proteins in the small intestine?
a. Lipids are absorbed into a capillary; carbohydrates and proteins are absorbed into a lacteal.
b. Lipids are not absorbed in the small intestine.
c. Lipids are absorbed into a lacteal; carbohydrates and proteins are absorbed into a capillary.
d. They are all absorbed into the same structure.
Problem 8
Match the following terms with the correct definition.
__Chief cells
__Parietal cells
__Gastrin
__Pyloric sphincter
__Diffuse neuroendocrine (DNES) cells
__Gastroesophageal sphincter
__Pepsin
__Chyme
a. Hormone that stimulates multiple digestive processes
b. Enzyme that begins protein digestion
c. Produce acid and intrinsic factor
d. Liquid produced as a result of stomach churning
e. Produce pepsinogen
f. Cells in gastric glands that produce hormones
g. Controls passage of bolus from esophagus to stomach
h. Controls passage of stomach contents to duodenum
Problem 9
What are the three folds of the small intestine called? What is their purpose?
Problem 10
Which of the following statements about accessory organ secretions is not true?
a. Hepatocytes produce bile, which drains out of the liver via the common hepatic ducts.
b. Saliva contains secretory IgA and lysozyme, which play an important role in preventing the growth of pathogenic bacteria in the oral cavity.
c. Pancreatic juice contains digestive enzymes and bicarbonate ions to neutralize the acidic chyme.
d. The gallbladder produces bile, which drains out of the gallbladder via the cystic duct.
Problem 13
Which of the following best describes the microscopic structure of the liver?
a. Hexagonal plates of hepatocytes surrounding a central vein with portal triads at each corner
b. Octagonal plates of hepatocytes surrounding a central artery with portal triads at each corner
c. Irregular groups of hepatocytes surrounding a central vein with bile ducts at each corner
d. Hexagonal plates of hepatocytes surrounding a portal vein with bile ducts at each corner
Problem 14b
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
b. The esophageal and pharyngeal phases of swallowing are mediated by the swallowing reflex of the brainstem and the enteric nervous system.
Problem 14c
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
c. Smooth muscle of the stomach contracts when food enters from the esophagus.
Problem 14e
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
e. During feeding, the small intestine exhibits motion in the migrating motor complex pattern.
Problem 15
Which of the following best describes the role of bile salts in lipid digestion?
a. Bile salts begin chemical digestion of lipids.
b. Bile salts bind to lipids and physically break them apart into monoglycerides and free fatty acids.
c. Bile salts bind to lipids and physically break them apart into smaller pieces.
d. Bile salts interact with pancreatic lipase and catalyze lipid breakdown.
Problem 16
The common hepatic duct and main pancreatic duct enter into the:
a. Pyloric sphincter
b. Duodenum
c. Ileum
d. Cecum
Problem 17
Lipids associate with bile salts in the small intestine to form_____ . In the enterocyte, lipids are packaged with other lipids into______.
Problem 18
Which of the following occurs/occur during the cephalic phase of gastric acid secretion?
a. Stimulation of gastrin and histamine release
b. Direct stimulation of parietal cells
c. Inhibition of somatostatin release
d. Both a and b are correct
e. All of the above are correct
Problem 20
The peritoneal cavity is located:
a. Around each of the digestive organs
b. Between layers of mesentery
c. Superior to the greater omentum
d. Between the parietal and visceral peritoneum
Problem 22d
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
The exocrine cells of the pancreas and salivary glands are islet cells.
Ch. 22 The Digestive System