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I) Draw the major stereoisomer formed in the E2 reaction of the following alkyl halide with the methoxide ion.
II) Would the product differ depending on whether the reactant was an (R) or (S) enantiomer?
Two alkenes (1,3-dimethyl-2-methylenecyclopentane and 1,2,3-trimethylcyclopent-1-ene) are formed by the elimination reaction of 1-bromo-1,2,5-trimethylcyclopentane with a strong base. Which of the following base would yield:
a. The highest percentage of 1,3-dimethyl-2-methylenecyclopentane?
b. The highest percentage of 1,2,3-trimethylcyclopent-1-ene?
Determine the major product for the elimination reaction given below. Show the resulting stereochemistry if necessary.
Draw the stereoisomer obtained in the greatest yield when 4-ethyl-4-iodo-3-methylheptane reacts via the E2 mechanism.
Give the products of E1 elimination of (Ph)3C−CH(CH3)Br. Identify the major products obtained in the reaction.
Provide a possible major product for the elimination reaction below. Note: Pay attention to stereochemistry.
Two different alkenes are produced in the reaction between 2-bromo-3-phenylpentane and sodium methoxide.
If the Zaitsev product predominates, determine the identity of the major and minor products and draw the reaction.