Compare and arrange these compounds in increasing order of acidity. Provide a suitable reason for your answer.
CH3CH2OH, HCOOH, HCl, HBr, CH4, and CH3CH(Cl)COOH
Identify the substituents in each of the following compounds as inductively electron-withdrawing, electron-donating by hyperconjugation, electron-withdrawing by resonance, or electron-donating by resonance.
a. —Cl
b. —CH3
c. —CHO
Consider the following nitrogenous compounds. Rank these compounds in order of increasing basic strength. Use the concept of hybridization. Additionally, rank their conjugate acids in order of decreasing acidic strength.
Identify the stronger base in each pair.
Rank the following compounds in order of decreasing acidity.
Which is a more stable conjugate base in the following pair of structures? Provide the basis for your answer.
Shown below are the structures of drugs and the diseases they treat. Predict whether the activity of these drugs will increase, decrease, or not be affected when taken with medicine for acid reflux diseases.