Using electron-pushing arrows, propose the mechanism for the E2 reaction shown below.
a. Explain why both SN2 and SN1 reactions are not feasible for 1-(chloromethyl)-1-isopropylcyclohexane.
b. Are E2 and E1 reactions feasible for it?
Draw the mechanism for the following E2 reaction.
Identify whether the following conditions will favor or disfavor an E2 reaction with neutral reactants.
i. strong base
ii. polar protic solvent
iii. increasing the concentration of the base
Determine the products for the E2 reaction of 3-bromo-2,2,3-trimethylhexane and CH3O−. Indicate the configuration if applicable.
The elimination reactions of the cis-1-iodo-4-isopropylcyclohexane and trans-1-iodo-4-isopropylcyclohexane with sodium methoxide in methanol form 4-isopropylcyclohex-1-ene. Explain the reason why the cis-1-iodo-4-isopropylcyclohexane is more reactive than the trans-1-iodo-4-isopropylcyclohexane.