Match the terms (1) active site, (2) lock-and-key model, and (3) induced-fit model with the following descriptions:
a. the portion of an enzyme where catalytic activity occurs
b. the active site adapts to the shape of a substrate
c. the active site has a rigid shape

Question

Match the terms (1) active site, (2) lock-and-key model, and (3) induced-fit model with the following descriptions:

a. the portion of an enzyme where catalytic activity occurs

b. the active site adapts to the shape of a substrate

c. the active site has a rigid shape

Accepted Answer

Hi, everyone. Our next question says which of the following statements are true. Regarding the active site lock and key model and Induced Fit model of enzymes. We have four different statements. We'll work our way through and then four different answer choices. A one and two, B one and three, C 12 and three or D 13 and four. So let's work our way through these sentences. Statement A or statement. One says the active site of an enzyme is a rigid structure that perfectly fits the substrate in the lock and key model. And this is indeed true. We have a slightly different understanding of that now. But initially, the specificity of the enzyme for the substrate, its ability to catalyze reactions was thought to be the best way to explain how enzymes did what they did. Um We now know that this is not really the best way, but it was a useful first model. So if statement one is correct, then that doesn't help us all of our answer choices have one in them. Step two says the induced fit model suggested the enzyme's active sight undergoes a confirmational change upon substrate binding to better fit the substrate. And this is also true that while lock and key, just as you know, your lock and key at home, always remains the same shape to always fit the same key. The induced fit model says you have an initial binding, an additional fitting of the substrate. And then you actually have a confirmational change that causes it to bind more tightly. So one and two both true. So we're down to either A or C is the only choices that have two in them. So cross out B which is one and three, cross out D which is 13 and four. Statement three says the lock and key model accounts for the enzyme's ability to adapt its structure to different substrates. Well, if the structure is adapting to different substrates, it means it's changing. So this is not going to be the lock and key model, but the induced Fit model. So statement three is incorrect and, but that doesn't help us with our answer choices or actually let's see, let's just rule out choice C 12 and three. So there we go, we don't need to go any further to get our answer of one and two. But since this is a practice problem, we'll be a little more thorough. Look at statement four which says in the induced fit model, the enzyme's active site is rigid and does not change shape during substrate binding. Well, pretty easy to tell that that is not going to be true compared to lock and key, which will be rigid and unchanging. So once again, if we're talking about the binding of an enzyme with its substrate, then the statements that are true are choice a statements. One and two. See you in the next video.

Match the terms (1) active site, (2) lock-and-key model, and (3) induced-fit model with the following descriptions:
a. the portion of an enzyme where catalytic activity occurs
b. the active site adapts to the shape of a substrate
c. the active site has a rigid shape

Verified video answer for a similar problem:

Key Concepts

Active Site

Lock-and-Key Model

Induced-Fit Model

Match the terms (1) active site, (2) lock-and-key model, and (3) induced-fit model with the following descriptions:a. the portion of an enzyme where catalytic activity occursb. the active site adapts to the shape of a substratec. the active site has a rigid shape

Verified video answer for a similar problem:

Key Concepts

Active Site

Lock-and-Key Model

Induced-Fit Model

Match the terms (1) active site, (2) lock-and-key model, and (3) induced-fit model with the following descriptions:
a. the portion of an enzyme where catalytic activity occurs
b. the active site adapts to the shape of a substrate
c. the active site has a rigid shape