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Problem 1a
In this chapter, we focused on the regulation of gene expression in eukaryotes. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter:
How do we know that transcription and translation are spatially and temporally separated in eukaryotic cells?
Problem 1b
In this chapter, we focused on the regulation of gene expression in eukaryotes. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter:
How do we know that DNA methylation is associated with transcriptionally silent genes?
Problem 1c
In this chapter, we focused on the regulation of gene expression in eukaryotes. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter:
How do we know that core-promoter elements are important for transcription?
Problem 1d
In this chapter, we focused on the regulation of gene expression in eukaryotes. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter:
How do we know that the orientation of promoters relative to the transcription start site is important while enhancers are orientation independent?
Problem 1e
In this chapter, we focused on the regulation of gene expression in eukaryotes. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter:
How do we know that alternative splicing enables one gene to encode different isoforms with different functions?
Problem 1f
In this chapter, we focused on the regulation of gene expression in eukaryotes. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter:
How do we know that small noncoding RNA molecules can regulate gene expression?
Problem 2
Write a short essay describing which types of trans-acting proteins bind to which type of cis-regulatory element, and how these interactions influence transcription initiation.