Table of contents

1. Intro to General Chemistry3h 48m
2. Atoms & Elements4h 16m
3. Chemical Reactions4h 10m
4. BONUS: Lab Techniques and Procedures1h 38m
5. BONUS: Mathematical Operations and Functions48m
6. Chemical Quantities & Aqueous Reactions3h 53m
7. Gases3h 49m
8. Thermochemistry2h 37m
9. Quantum Mechanics2h 58m
10. Periodic Properties of the Elements3h 9m
11. Bonding & Molecular Structure3h 29m
12. Molecular Shapes & Valence Bond Theory1h 57m
13. Liquids, Solids & Intermolecular Forces2h 23m
14. Solutions3h 1m
15. Chemical Kinetics2h 53m
16. Chemical Equilibrium2h 29m
17. Acid and Base Equilibrium5h 1m
18. Aqueous Equilibrium4h 47m
19. Chemical Thermodynamics1h 50m
20. Electrochemistry2h 42m
21. Nuclear Chemistry2h 36m
22. Organic Chemistry5h 7m
23. Chemistry of the Nonmetals2h 39m
24. Transition Metals and Coordination Compounds3h 16m

22. Organic Chemistry

Ester Reactions: Esterification

General Chemistry

22. Organic Chemistry

Ester Reactions: Esterification

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Multiple Choice

Aspirin also known as acetylsalicyclic acid possesses an ester group that is formed from the reaction between ethanoic acid and salicyclic acid. Determine the structure of aspirin after the condensation between ethanoic acid and salicyclic acid.

Chemical reaction diagram illustrating the esterification process for aspirin synthesis.

Molecular structure of salicylic acid, a precursor in aspirin synthesis.

Chemical structure of ethanoic acid, used in the formation of aspirin.

Esterification reaction mechanism for the formation of aspirin from salicylic and ethanoic acid.

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Verified step by step guidance

Identify the functional groups in both reactants: Ethanoic acid (acetic acid) has a carboxylic acid group (-COOH), and salicylic acid has both a carboxylic acid group and a phenolic hydroxyl group (-OH).

Recognize that the esterification reaction involves the reaction between the hydroxyl group of salicylic acid and the carboxylic acid group of ethanoic acid.

During the esterification process, the hydroxyl group (-OH) from the salicylic acid and the hydrogen atom (H) from the carboxylic acid group of ethanoic acid are removed to form water (H2O).

The remaining oxygen atom from the salicylic acid's hydroxyl group forms a bond with the carbon atom of the carbonyl group (C=O) from ethanoic acid, creating an ester linkage (R-COO-R').

The resulting structure of aspirin (acetylsalicylic acid) will have an ester group (R-COO-R') where the salicylic acid's hydroxyl group was, and the rest of the salicylic acid structure remains unchanged.