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Multiple Choice
What is the most abundant anion in the extracellular fluid (ECF)?
A
Sulfate (SO₄²⁻)
B
Phosphate (PO₄³⁻)
C
Bicarbonate (HCO₃⁻)
D
Chloride (Cl⁻)
Verified step by step guidance
1
Understand the context: The extracellular fluid (ECF) is the fluid outside of cells, which includes interstitial fluid, blood plasma, and lymph. It plays a crucial role in transporting nutrients and waste products.
Identify the common anions in the ECF: The major anions present in the ECF include chloride (Cl⁻), bicarbonate (HCO₃⁻), sulfate (SO₄²⁻), and phosphate (PO₄³⁻).
Consider the physiological role and concentration: Chloride ions (Cl⁻) are essential for maintaining osmotic balance and are the most abundant anions in the ECF, contributing significantly to the osmolarity of the fluid.
Compare the concentrations: Chloride (Cl⁻) is present in much higher concentrations in the ECF compared to other anions like bicarbonate (HCO₃⁻), sulfate (SO₄²⁻), and phosphate (PO₄³⁻).
Conclude based on the information: Given its high concentration and essential role in maintaining osmotic pressure, chloride (Cl⁻) is the most abundant anion in the extracellular fluid.