Problem L2.1a
Eileen presents with flu-like symptoms, including fever, chills, and body aches.
What part of the immune response is likely producing these symptoms?
Problem L2.1b
Eileen presents with flu-like symptoms, including fever, chills, and body aches.
You order blood work and find that the number of neutrophils in the blood is greatly elevated. What does this tell you about the likely type of pathogen involved? Explain.
Problem L2.1c
Eileen presents with flu-like symptoms, including fever, chills, and body aches.
c. What might it mean if lymphocytes instead of neutrophils were elevated? Explain your reasoning.
Problem L2.2
Complement proteins are crucial for stimulating phagocytes to clear immune complexes. Predict what type of hypersensitivity disorder might result from complement deficiencies. Explain what other consequences might arise from a complement deficiency.
Problem L2.3
Terrence has severe asthma and allergies, and is placed on a medication that blocks the functioning of IgE. How would this medication alleviate his symptoms?
Problem L3.1
Your friend tests her snake-wrangling skills on an eastern diamondback rattlesnake, and is bitten and envenomated (injected with the snake's venom). In the emergency department, doctors administer the antivenin CroFab, which contains antibodies to the toxins in snake venom. Is this an example of active or passive immunity? Will this confer any lasting protection to your friend?
Problem L3.2a
Carla presents to her physician with a complaint of swollen axillary lymph nodes. Her physician performs a breast exam and finds a tumor on the same side as the swollen nodes.
a. Explain what process has likely caused her nodes to swell.
Problem L3.2b
Carla presents to her physician with a complaint of swollen axillary lymph nodes. Her physician performs a breast exam and finds a tumor on the same side as the swollen nodes.
b. Carla undergoes surgery to have the tumor and affected lymph nodes and surrounding lymphatic vessels removed. Predict any complications Carla might have after the surgery that could arise from removal of the lymph nodes and vessels.
Problem L3.3
Mr. White has been diagnosed with febrile neutropenia, a condition characterized by the presence of a fever with an extremely low number of neutrophils in the blood. Blood work demonstrates the presence of bacteria in his blood. Explain why neutropenia might lead to a bacterial infection. Why is a bacterial infection particularly dangerous for Mr. White?
Problem L3.4
Mr. White developed neutropenia as a consequence of cancer chemotherapy, which destroyed much of his bone marrow. What other components of the immune system would be harmed by bone marrow destruction? Would you expect his hematocrit to be elevated or decreased? What effects would you expect to see from this change in hematocrit?
Problem L3.5
The chemotherapeutic drugs Mr. White is taking affect all cells that undergo rapid mitosis, such as those of the skin. What effect would this have on the functions of the skin? How could this affect his immunity?
Ch. 20 The Lymphatic System and Immunity